Giuseppe Carluccio1,2, Yu-Shin Ding1,2, Jean Logan1,2, and Christopher Michael Collins1,2
1Radiology, Center for Advanced Imaging Innovation and Research (CAI2R), New York, NY, United States, 2Radiology, Bernard and Irene Schwartz Center for Biomedical Imaging, New York, NY, United States
We
explore
the possibility that SAR-related temperature increase could affect
metabolic rates enough to alter FDG signal in MR/PET. Using numerical
simulations, we calculate the distributions of SAR, temperature,
metabolic rates, FDG concentration ([FDG]), and PET
signal throughout the human body. Calculation of [FDG] utilizes a
two-compartment model considering metabolic rate through time. Results
are calculated for injection time one hour before the onset of imaging
and for injection time simultaneous with the onset of imaging. Even
for worst-case scenario (max allowable whole-body SAR for the duration
of the scan), there is little observable effect on PET signal.