1Dept. of Radiology - Medical Physics, University Medical Center Freiburg, Freiburg, Germany, 2German Cancer Consortium (DKTK), Heidelberg, Germany, 3German Cancer Research Center (DKFZ), Heidelberg, Germany, 4Institute of Microstructure Technology, Karlsruhe Institute of Technology, Karlsruhe, Germany, 5Department of Neuroradiology, Neurocenter, University Medical Center Freiburg, Freiburg, Germany