Mark J. van Uden1, Bart Philips1, Miriam Lagemaat1, and T.W.J. Scheenen1,2
Multiparametric
MRI (mpMRI) is a valuable tool to assess
aggressiveness and stage of localized prostate cancer. When combined with
metabolic information from 1H and 31P spectra valuable
information on the metabolism of the disease can be derived. Here we
demonstrate a dual element endorectal coil with 1H Rx and 31P
TxRx capabilities combined with an external 8-channel transmit-receive body
array. One patient (Gleason score 4+4) was measured. High quality proton
spectra show elevated total choline in tumor tissue, which corresponded with
increased glycerophosphocholine, glycerophosphoethanolamine and phosphocholine in
the 31P spectra of the tumor.
