In this
study, an automatic optimization scheme was proposed in diffusion-weighted
imaging using simultaneous multi-slice (SMS) acceleration to determine an
appropriate flip angle based on a short TR, which is capable to obtain similar
contrast of a pair of tissue type compared to the one with long TR scan. With
this optimization scheme, minimal TR in SMS case is practically achievable and there is no obvious contrast deviation between images from
long TR (FA = 900) and short TR (FA < 900).