Abstract #3373

Transient Changes in White Matter Microstructure during Anesthesia

Cheuk Ying Tang¹, Victoria X Wang², Johnny C Ng², Stacie Deiner³, Rafael O'Halloran², Patrick McCormick³, Prantik Kundu², Lazar Fleysher², Angela Sanchez³, Kleopoulos Steven⁴, and Mark Baxter⁵

¹Radiology & Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ²Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Anesthesiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ⁴Icahn School of Medicine at Mount Sinai, New York, NY, United States, ⁵Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, United States

The effect of general anesthesia was studied in brain white matter of healthy control elderly subjects. DTI measures were compared between awake and general anesthesia conditions. We found significant transient decreases in Fractional Anisotropy and increases in Mean Diffusivities throughout the brain.

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