Weiying Dai1,2, Li Zhao1, and David Alsop1
1Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States, 2Computer Science, State University of New York at Binghamton, Binghamton, NY, United States
ASL global signal
fluctuations, uniformly correlated across gray matter, may
reflect globally correlated neural activity that would suggest a global resting
network. However, physiological noise, such as cardiac and respiratory motion,
could potentially contribute to the global signal fluctuations. Our results
indicate that the systemic noise does not contribute to the ASL global signal
fluctuation significantly. Global signal fluctuations are the dominant resting
fluctuations of the ASL signal, suggesting a separate globally correlated
resting state network in addition to those region-specific resting state networks.
