Abstract #3324

Characterizing Cerebral Arterial Pulsatility and Flow Waveforms from the Proximal Internal Carotid Artery to Distal Middle Cerebral Artery in Adult Volunteers Using 4D Flow MRI

Liliana E. Ma¹, Can Wu^1,2, Susanne Schnell¹, Christophe Chnafa³, David Steinman³, and Michael Markl^1,2

¹Department of Radiology, Northwestern University, Chicago, IL, United States, ²Department of Biomedical Engineering, Northwestern University, Evanston, IL, United States, ³Department of Mechanical Engineering, University of Toronto, Toronto, ON, Canada

Characterization of cerebral arterial flow waveforms in healthy subjects can help establish a comparison baseline in studies of cerebrovascular disease and provide key inputs for computational fluid dynamic studies. The purpose of this study was to quantitatively characterize cerebral arterial waveforms in healthy adult subjects by extracting arterial pulsatility and flow waveforms along the ICA and MCA using 4D flow MRI. Our findings demonstrated no significant changes in arterial pulsatility from proximal ICA to distal MCA, although a decreasing trend was observed from the proximal to distal carotid siphon in young adults.

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