Wendy Harris1,2, Fang-Fang Yin1,2, Chunhao Wang1,2, Zheng Chang1,2, Jing Cai1,2, You Zhang1,2, and Lei Ren1,2
1Department of Radiation Oncology, Duke University, Durham, NC, United States, 2Medical Physics Graduate Program, Duke University, Durham, NC, United States
A
novel technique has been developed to generate ultra-fast high-quality
volumetric cine MRI (VC-MRI) using patient prior information. The VC-MRI was
generated by deforming the prior volumetric MRI images based on ultra-fast
on-board 2D-cine MRI and patient PCA-based respiratory breathing model. The ultra-fast
2D-cine images were acquired by sampling about 10% of k-space. The undersampled
cine images were reconstructed using an iterative MR reconstruction algorithm
with a total generalized variation penalty. The technique was evaluated using
both anthropomorphic digital phantom and patient data. Results demonstrated the
feasibility of generating ultrafast-VC-MRI for both inter-and intra-fraction
verification of moving targets in radiotherapy.
