Abstract #3160

Myocardial Local Frequency Shift Mapping

Junmin Liu¹, James W Goldfarb², and Maria Drangova^1,3

¹Imaging Research Laboratories, Robarts Research Institute, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada, ²Department of Research and Education, Saint Francis Hospital, Roslyn, NY, United States, ³Medical Biophysics, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada

Local Frequency Shift (LFS) mapping of the myocardium may provide information about the integrity and organization of myofibers, which contribute anisotropic magnetic susceptibility. We present a myocardial LFS mapping method by explicitly removing the unwanted phase terms caused by B0 inhomogeneity and chemical-shift (CS) between fat and water. The proposed method was tested with human data and compared with the established high-pass filtering technique. The results demonstrate a gradient across the myocardial wall suggesting that LFS maps of the myocardium may enable visualization of myofiber orientation.

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