Laura Claire Saunders1, Neil J Stewart1, Charlotte Hammerton1, David Capener1, Valentina O Puntmann2, David G Kiely3, Martin J Graves4, Andy Swift1, Jim M Wild1, and Laura Claire Saunders1
1Academic Unit of Radiology, The University of Sheffield, Sheffield, United Kingdom, 2Department of Cardiovascular Imaging, Kings College London, London, United Kingdom, 3The University of Sheffield, Sheffield, United Kingdom, 4University of Cambridge School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom
Patients with pulmonary hypertension (n=102, 58±16 years,
56% female) and age and sex matched volunteers (n=34, 51±14 years, 58% female)
underwent functional cardiac MR and MOLLI T1 mapping at 1.5T. MOLLI images were
registered to correct for respiratory motion. Patients had elevated myocardial
T1 at the right ventricular (RV) insertion point (p<0.001) and left
ventricular free wall when compared to healthy volunteers (p=0.013). RV
insertion point T1 and pulmonary artery pressure correlated significantly (r=0.406
p=0.016). Correlations were found between RV free wall and septal T1 and
diastolic mass index (corrected for age and sex) (r=0.305, p=0.003 and r=0.281,
p=0.006 respectively).
Patients with pulmonary hypertension (n=102, 58±16 years,
56% female) and age and sex matched volunteers (n=34, 51±14 years, 58% female)
underwent functional cardiac MR and MOLLI T1 mapping at 1.5T. MOLLI images were
registered to correct for respiratory motion. Patients had elevated myocardial
T1 at the right ventricular (RV) insertion point (p<0.001) and left
ventricular free wall when compared to healthy volunteers (p=0.013). RV
insertion point T1 and pulmonary artery pressure correlated significantly (r=0.406
p=0.016). Correlations were found between RV free wall and septal T1 and RV mass index (corrected for age and sex) (r=0.305, p=0.003 and r=0.281,
p=0.006 respectively).
