Rui Guo1, Zhensen Chen1, Jianwen Luo1, and Haiyan Ding1
In this study, we developed a free-breathing,
three-dimensional (3D) T1 mapping method at 3T based on the saturation-prepared,
inversion-prepared radiofrequency-spoiled gradient echo (SPGR) sequence, which
achieved 3D T1 maps with whole heart coverage. Excellent correlation for the T1
values typically observed in myocardium pre and post contrast was obtained
with little residual (R2 = 0.99) and a regression slope 0.93. Homogeneous T1
maps were obtained from in-vivo study. Whole left ventricle T1 mapping was finished
in around ~10 minutes with about 40% navigator efficiency without using any
parallel imaging. Measured normal myocardium T1 values were comparable to those
previously published.