Abstract #3149

Ungated, Free-breathing Native T1 Mapping in Multiple Cardiac Phases in Under One Minute: A Proof of Concept

Jaime L. Shaw^1,2, Anthony G. Christodoulou^1,3, Behzad Sharif¹, and Debiao Li^1,2

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, ³Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

Current cardiac T1 mapping techniques are generally limited to single-shot 2D images acquired in a breath hold with ECG gating. Heart rate variability or poor ECG triggering are sources of error and reduced reproducibility in the widely used MOLLI T1 mapping technique. To mitigate the dependence of T1 mapping on heart rate and breath-holds, we propose an ungated, free-breathing, continuous IR approach using low-rank tensors modeling the image as partially separable in space, cardiac phase, respiratory phase, and inversion time. We show the feasibility of the ungated, free-breathing approach in producing T1 maps in multiple cardiac phases in under 1 minute.

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