1Radiology, UCAIR, University of Utah, Salt Lake City, UT, United States, 2Bioengineering, University of Utah, Salt Lake City, UT, United States
Patients
with end-stage heart failure (HF) often require advanced therapeutics, but
current clinical profiles and biomarkers are not adequate for predicting
outcomes. Myocardial perfusion reserve may be an important predictor, but it is
technically challenging to perform perfusion MRI in patients with end-stage HF
because they often have implantable cardioverter defibrillator (ICD), which
generates significant image artifacts. We developed a novel cardiac perfusion
pulse sequence using a wideband saturation pulse. Compared with standard
perfusion MRI, wideband perfusion MRI suppresses image artifacts induced by
ICD.