Abstract #3123

Short-breath hold cine DENSE

Andrew David Scott^1,2, Upasana Tayal^1,2, Sonia Nielles-Vallespin^1,3, Pedro Ferreira^1,2, Xiaodong Zhong⁴, Frederick Epstein⁵, Sanjay Prasad^1,2, and David Firmin^1,2

¹NIHR funded Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom, ²National Heart and Lung Institute, Imperial College London, London, United Kingdom, ³National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States, ⁴MR R&D Collaborations, Siemens Healthcare, Atlanta, GA, United States, ⁵University of Virginia, Department of Biomedical Engineering, Charlottesville, VA, United States

Displacement encoding with stimulated echoes (DENSE) can provide valuable strain information, but acquisitions are typically too long for patient cohorts who have difficulty breath holding. In this work we accelerate 2D cine spiral DENSE acquisitions by selectively exciting a small field of view around the heart. We compare strain data derived from DENSE acquired with unaccelerated and up to 2.5x acceleration in a cohort of healthy subjects and show minimal differences when the acquisition is accelerated. We also show an example from a patient with a myocardial infarction where the accelerated DENSE data shows abnormal strain in the infarcted regions.

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