Abstract #3096

Intravoxel Incoherent Motion in Normal Pituitary Gland: Initial Study with Turbo Spin-echo Diffusion-weighted Imaging

Kiyohisa Kamimura¹, Masanori Nakajo¹, Yoshihiko Fukukura¹, Takashi Iwanaga², Tomonori Saito², Masashi Sasaki², Takuro Fujisaki², Atsushi Takemura³, Tomoyuki Okuaki ³, and Takashi Yoshiura¹

¹Radiology, Kagoshima University Medical and Dental Hospital, Kagoshima, Japan, ²Clinical Engineering Department Radiation Section, Kagoshima University Hospital, Kagoshima, Japan, ³Philips Electronics Japan, Tokyo, Japan

Our purpose was to evaluate the feasibility of intravoxel incoherent motion (IVIM) assessment based on turbo spin-echo diffusion-weighted imaging (TSE-DWI) in the normal pituitary gland. In a validation study using normal brain white matter (WM), Bland-Altman analyses revealed fair to good agreement with conventional echo-planar-based DWI (EP-DWI) in the true diffusion coefficient (D) and perfusion fraction (f). In 7 volunteers, both D and f in the anterior pituitary lobe were significantly higher than those in WM, being consistent with high microvascular density in the pituitary gland. Results demonstrated that IVIM assessment based on TSE-DWI in the pituitary gland is feasible.

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