1School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, GuangZhou, China, People's Republic of, 2Philips Healthcare, GuangZhou, China, People's Republic of, 3Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, GuangZhou, China, People's Republic of, 4Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China, People's Republic of, 5Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China, People's Republic of