Sean Foxley1, Saad Jbabdi1, Moises Hernandez Fernandez1, Connor Scott2, Olaf Ansorge2, and Karla Miller1
1FMRIB Centre, University of Oxford, Oxford, United Kingdom, 2Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
In this
work we compare a single flip angle and dual flip angle approach to overcome B1
inhomogeneities in DW-SSFP data of post mortem human brain at 7T. Both
approaches were designed and optimized to achieve optimal CNR with whole brain
coverage. The single flip angle approach displayed slight improvements in
orientation estimates; however, the dual flip angle approach is being further
investigated as a potential source of microstructural estimates with little to
no cost in orientation.