Abstract #3061

A novel diffusion tensor imaging phantom that simulates complex neuro-architecture for potential validation of DTI Processing

Greg Whitton¹, Timotheus Gmeiner¹, Chad Tyler Harris¹, and Fergal Kerins¹

¹Synaptive Medical, Toronto, ON, Canada

In this work a DTI phantom containing complex geometries and anisotropic microstructure to mimic fiber bundles is presented. The phantom consists of ten individual fiber bundles distributed in different orientations to best test and confirm proper DTI processing. Each fiber bundle contains 4.4 million fibers within a flexible casing. The phantom was imaged using a 2D EPI DTI sequence, and tractography was generated using BrightMatter™ Plan. Agreement was found between fiber location and tractography: FA values averaging 0.51, were within +/- 10% of the overall FA average within the fibers demonstrating consistent diffusion throughout the fiber bundles.

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