Yanyan Xu1, Hongliang Sun1, Kaining Shi2, and Wu Wang1
1Radiology, China-Japan Friendship hospital, Beijing, China, People's Republic of, 2Philips Healthcare China, Beijing, China, People's Republic of
Dynamic contrast-enhanced
magnetic resonance imaging (DCE-MRI) has been applied in rectal cancer for the
purpose of characterizing tumor perfusion[1]. However, DCE-MRI should use
intravenous contrast media based gadolinium, which will increase the risk of
kidney systemic fibrosis[2]. The bi-exponential analysis in intravoxel incoherent
motion (IVIM) model can separate microscopic circulation perfusion with pure
water diffusion[3-4]. Correlation has been derived between the IVIM perfusion
parameters f and D* and the classical perfusion parameters[5-6]. However, its
relationship with DCE-MRI parameters in rectal cancer has not been clarified.