The potential of arterial spin labeling with full labeling duty cycle (FDC-ASL) to measure blood flow and transit delay simultaneously with substantially improved sensitivity and efficiency
Jia Guo1, Richard B. Buxton1, and Eric C. Wong1,2
1Radiology, UC San Diego, La Jolla, CA, United States, 2Psychiatry, UC San Diego, La Jolla, CA, United States
Pulsed arterial spin labeling (PASL) has the potential
to achieve full labeling duty cycle with almost instant labeling. We explore here
a new PASL-based fast labeling and imaging method for measuring blood flow (BF)
and transit delay (TD) simultaneously, through a series of simulations. The
results show that the BF and the TD can be accurately estimated. This new approach
shows promise for substantially improved sensitivity and efficiency compared
with conventional methods using PASL or pseudo-continuous ASL.
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