Ning Lang1, Hon J. Yu2, Huishu Yuan1, and Min-Ying Su2
1Department of Radiology, Peking University Third Hospital, Beijing, China, People's Republic of, 2Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, United States
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patients with giant cell tumor in the spine and 12 patients with chordoma
received DCE-MRI were analyzed. The morphological features (lesion location,
vertebral compression, paraspinal soft tissue mass, bone expansion change,
fiber separation, and MR signal on T1W1 and T2W1) and DCE pharmacokinetic
parameters were compared. Several typical morphological features could be used
for differential diagnosis, but there was a substantial overlap. DCE-MRI may
provide very helpful information. Giant cell tumor had a significantly higher
Ktrans and kep compared to chordoma, and by using a cut-off value of
kep=0.43/min, it could achieve a very high accuracy of 95%.
