Masako Ohno1, Tosiaki Miyati2, Naoki Ohno2, Hiroko Kawashima2, Kazuto Kozaka1, Yukihiro Matsuura1, and Toshifumi Gabata1
To
acquire more detailed information on perfusion and diffusion in breast cancer,
we analyzed three diffusion components using triexponential function.
Perfusion-related
diffusion (Dp), fast free
diffusion (Df), and slow
restricted diffusion coefficients (Ds)
were calculated from triexponential function. We compared these parameters between
invasive ductal carcinoma (IDC) and ductal carcinoma in situ (DCIS) groups.
Ds was
significantly lower in the IDC group than those in the DCIS group because
of difference in the cellularity.
Triexponential
analysis makes it possible to noninvasively obtain more detailed information on
perfusion and diffusion in breast cancer, thereby assisting in the diagnosis.
