Akane Ohashi1, Masako Kataoka1, Syotaro Kanao1, Mami Iima1, Onishi Natsuko1, Makiko Kawai1, Masakazu Toi2, Elizabeth Weiland3, and Kaori Togashi1
1Department of Diagnostic Imaging and Nuclear Medicine, Kyoto Univercity Graduate School of Medicine, Kyoto, Japan, 2Breast Surgery, Kyoto Univercity, Kyoto, Japan, 3Siemens Healthcare GmbH, Erlangen, Germany
Maximum slope (MS) is a
kinetic parameter obtained from the very early phase of
ultrafast DCE MRI. Diagnostic performance of MS in breast lesions were compared
to washout index (WI), a conventional semi-quantitative kinetic parameters
obtained from standard DCE MRI. Ultrafast DCE MRI was obtained using KWIC and
analyzed by TWIST Breast Viewer. MS demonstrated significantly higher AUC (0.91)
than WI (0.80, p=0.03) with fewer false positive cases of fibrocystic changes
than WI. MS is a promising kinetic parameters that provides information
complimentary to WI in diagnosing breast lesions.
