Marc D Lindley1,2, Daniel Kim2, Kristi Carlston2, Leif Jensen2, Daniel Sommers2, Ganesh Adluru2, Edward VR DiBella2, Christopher J Hanrahan2, and Vivian S Lee2
1Physics, University of Utah, Salt Lake City, UT, United States, 2Radiology, UCAIR, University of Utah, Salt Lake City, UT, United States
Quadruple inversion-recovery (QIR), non-contrast (NC) MRA
was developed as an alternative to contrast-enhanced MRA, and it performance
was evaluated in patients with peripheral arterial disease. The scan time for QIR with respiratory gating,
however, is on the order of 10-15 minutes. We sought to accelerate QIR using a
combination of 3D radial stack-of-stars sampling with tiny golden angles and
compressed sensing (CS). This study shows that 5.3-fold accelerated QIR with
radial k-space sampling and CS produces images that are comparable to those
produced by original QIR (e.g., 2.7-fold acceleration using GRAPPA). In 10
human subjects, normalized signal difference and vessel dimensions were not
significantly different between original QIR and 5.3-fold accelerated QIR with
radial k-space sampling and CS.