Single-echo
Dixon imaging for contrast-enhanced MR angiography (CE-MRA) can provide the
advantages of multi-echo Dixon without the tradeoff of longer acquisitions and
reduced temporal resolution. Single-echo Dixon imaging assumes that both
the water and fat signals are real and have known initial phase and phase due
to field inhomogeneities. However, when a paramagnetic Gadolinium-based contrast agent is
injected for CE-MRA, the field may be perturbed and render the a priori phase
estimates invalid. The purpose of this study is to demonstrate the
effect of Gd-induced field perturbations on first-pass single-echo Dixon CE-MRA
and describe strategies to avoid or correct artifacts.