Accelerated MR Elastography for Quantitative Measurement of Myocardial Stiffness
Rizwan Ahmad1, Samuel Schroeder2, Richard D White3, and Arunark Kolipaka3
1Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States, 2Mechanical Engineering, The Ohio State University, Columbus, OH, United States, 3Radiology, The Ohio State University, Columbus, OH, United States
Alterations in myocardial stiffness have been
linked to wide-ranging cardiovascular conditions. Magnetic resonance
elastography (MRE) is a noninvasive, quantitative technique to estimate
stiffness of soft tissue.1 Long scan times, however, limit the
clinical utility of MRE, especially for cardiac imaging. We propose a data
processing technique that not only exploits sparsity in the MRE images but also
imposes a constant magnitude constraint to achieve accurate stiffness values
from highly undersampled data. The method is validated using a physical phantom
of known stiffness value and is then applied to a healthy volunteer to assess
myocardial stiffness.
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