Impaired myocardial resting perfusion in patients undergo chemo therapy, a quantitative MRI perfusion study
Yi Wang1
1St. Francis Hospital, Albertson, NY, United States
We
tried to develop and validate an early detection technique of chemo therapy
cardiotoxicity in the cancer treatment using cardiovascular magnetic resonance
imaging. We hypothesized myocardial blood flow (MBF), more sensitive
technique than EF or DHE, provides information on the altered physiology and
function conditions of the heart. Chemo treatment induces changes in myocardial
perfusion at rest enough to be detected with model based quantitation, with
sequential imaging on the same subject. It provides an earlier indication of
cardiotoxicity.
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