Abstract #2603

Fixed-Volume Particle Trace Emission for the Analysis of Left Atrial Blood Flow using 4D Flow MRI

Stephen Gaeta¹, Petter Dyverfeldt^2,3, Jonatan Eriksson^2,3, Carl-Johan Carlhäll^2,3, Tino Ebbers^2,3, and Ann F Bolger⁴

¹Department of Medicine, Duke University, Durham, NC, United States, ²Department of Medical and Health Sciences, Linköping University, Linköping, Sweden, ³Center for Medical Image Science and Visualisation (CMIV), Linköping University, Linköping, Sweden, ⁴Department of Cardiology, University of California San Francisco, San Francisco, CA, United States

The aim of this study was to develop a novel fixed-volume approach for particle tracing and employ this to develop quantitative analysis of 4D blood flow characteristics in the left atrium (LA). The proposed fixed volume approach for emission of particle traces permits sampling of LA blood volumes and intuitive visualizations where each trace represents the same volume. Using fixed-volume particle traces, LA flow can be separated into different components based on the transit of blood through the LA. Quantitative analysis of functionally distinct subsets of LA flow may provide new perspectives on LA function in health and disease.

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