Da Wang1,2, Jiaxin Shao1, Daniel B Ennis1,2, and Peng Hu1,2
1Radiology, University of California, Los Angeles, Los Angeles, CA, United States, 2Biomedical Physics, University of California, Los Angeles, Los Angeles, CA, United States
In conventional 4D-flow phase-contrast MRI, each cardiac phase acquires the flow-compensated and three-directional
flow-encoded echoes, which often limits the achievable temporal-resolution and
temporal-footprint. This can result in under-estimation of maximum peak
velocity. Herein, we propose a fast 4D-flow strategy that eliminates the flow-compensated
acquisition using hybrid one- and two-sided flow encoding only (HOTFEO). The flow-compensated background phase is derived from three-directional flow-encoded data based on a velocity direction constraint that assumes the velocity direction, not the magnitude,
changes very little between two cardiac phases. HOTFEO provides accurate blood
flow and velocity measurements compared with conventional 4D-flow technique.