Abstract #2541

Assessment of Myocardial B0 over the Cardiac Cycle at 7.0T: Implications for Susceptibility-based CMR Techniques

Teresa Serradas Duarte¹, Till Huelnhagen¹, and Thoralf Niendorf^1,2

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center in the Helmholtz Associaiton, Berlin, Germany

Magnetic susceptibility-based methods are an emerging technique in CMR for myocardial tissue characterization. Making use of UHF MRI, temporally resolved myocardial T₂^* mapping was recently demonstrated. Since susceptibility weighted MRI is highly dependent on main magnetic field homogeneity, B₀ assessment is crucial for interpretation of results. This pioneering study investigates B₀ variation in the heart over the cardiac cycle at 7.0T and its implications for myocardial T₂^* mapping in a cohort of healthy volunteers. Results show that septal macroscopic field inhomogeneities are minor regarding their effects on T₂^*. This provides encouragement for temporally resolved susceptibility-based CMR at UHF.

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