Abstract #2493

A Fast Method for Simultaneous ADC and T2 Mapping Using Spin Echo EPI Sequence

Minxiong Zhou^1,2, Xu Yan³, Ming Deng⁴, Zan Ke⁴, Xiangde Min⁴, Caixia Fu⁵, Hui Liu³, Alto Stemmer⁶, and Liang Wang⁴

¹Shanghai University of Medicine & Health Sciences, Shanghai, China, People's Republic of, ²Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University of Medicine, China, Shanghai, China, People's Republic of, ³MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China, Shanghai, China, People's Republic of, ⁴Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, People's Republic of, ⁵Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, People's Republic of, ⁶Siemens Healthcare, Erlangen, Germany

This study proposes a fast SE-EPI-based method to simultaneously acquire ADC and T2 maps using dataset with multiple b-values and multiple TE values, which can be acquired in around 3 minutes. This method was validated using a group of prostate data, showing that the T2 maps generated by the proposed method were comparable to those by a conventional TSE-based method. In addition, both T2 and ADC showed significant differences between prostate cancer and benign prostatic hyperplasia, indicating that joint usage of ADC and T2 mapping might potentially help in tumor differentiation in difficult cases in addition to ADC alone. Furthermore, this method is intrinsically free of registration and misalignment artifacts between ADC and T2 and can also be integrated with other diffusion models such as IVIM, DKI.

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