Josephin Otto1, Alexander Schaudinn1, Simone Mucha1, Nicolas Linder1, Nikita Garnov1, Jens-Uwe Stolzenburg2, Lars-Christian Horn3, Thomas Kahn1, Michael Moche1, and Harald Busse1
1Diagnostic and Interventional Radiology Department, Leipzig University Hospital, Leipzig, Germany, 2Urology Department, Leipzig University Hospital, Leipzig, Germany, 3Institute of Pathology, University of Leipzig, Leipzig, Germany
Multiparametric
MRI of the prostate has substantially improved the detection of clinically
significant prostate cancer (PCa) and the confidence in benign and
insignificant findings. The recent v2.0 update of the Prostate Imaging
Reporting and Data System (PIRADS) has replaced the sum of individual MRI sequence
scores (1-15 or 1-20) with a zone-dependent, dominant MRI sequence (DWI in the
peripheral and T2W in the transition zone) with an overall score from 1-5. The
aim of this preliminary study was the blinded comparison of both versions for
the detection of PCa on the same patients using whole-mount histological workup
as gold standard.