Abstract #2469

Three-time point method of dynamic contrast-enhanced MRI in discrimination of ACTH-producing and non-functional pituitary adenomas based on whole-tumor quantification

Miaomiao Wang¹, Chao Jin¹, Jianxin Guo¹, Lihong Chen¹, Tingting Qu¹, Hui Hao¹, and Jian Yang¹

¹Department of Radiology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China, People's Republic of

Quantitative characterizations of functional vascularity of ACTH-producing and non-functioning pituitary adenomas are critical to identify their differences in clinics. From this, a semi-quantitative method, i.e. three-time point method of DCE-MRI was proposed to detail the dynamic enhanced features and thus distinguish them. The results indicate that based on the enhancement time-signal curve, the volume percentage of the two groups are different in the washout-type curve. Particularly, in wash-out phase of the curve, the descending slope of ACTH-producing is greater than that in non-functioning pituitary adenoma.

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