Timothy James Pengilley Bray1, Saurabh Singh1, Arash Latifoltojar1, Kannan Rajesparan1, Farzana Rahman1, Alan Bainbridge2, Shonit Punwani1, and Margaret A Hall-Craggs1
1Centre for Medical Imaging, University College London, London, United Kingdom, 2Medical Physics, University College London, London, United Kingdom
Dixon
imaging is becoming more widely used in multiple myeloma (MM) and can provide
both functional and anatomical information. We observed that myeloma lesions
seemed more conspicuous on fat only (FO) images than on conventional in-phase
T1, and therefore hypothesised that lesion detection rates would be higher on
FO images. In this research, we show that reader sensitivity, positive
predictive value and confidence are indeed higher on FO images. This may be
because myeloma lesions cause a proportionately greater change in fat content
than in water content. We suggest that Dixon imaging should be used in
preference to T1 imaging alone when performing WB-MRI.
