Abstract #2441

Quantification of transverse relaxation time changes in rectal tissue during fixation at ultra-high field MRI

Quincy van Houtum¹, Dennis D.W.J. Klomp¹, and Marielle M.E.P. Philippens¹

¹Imaging, UMC Utrecht, Utrecht, Netherlands

In this study we investigate the transverse relaxation effects at 7T during the fixation process in rectal specimens as a preparation for 7T MRI validation of rectal tumor regression with pathology. T2 and T2* were measured every 2 hours during fixation process in six different pig recta. Images allowed mapping of relaxation time at high spatial resolution. The circular muscle showed a decrease of 25% in T2* whilst other tissues remained constant over time for both parameters. A T2* decrease of 25% is seen in the circular muscle of the rectal wall was noticed whilst other tissue-regions remained constant. High resolution and SNR allowed for anatomical delineation and measuring the change of transverse relaxation times.

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