There is increasing need of a more human cell model to recapitulate the in-vivo cell-cell interactions,
presenting physiological relevance. Magnetic resonance spectroscopy (MRS) has
the potential to diagnose many tumors and to characterize their metastatic
potential. In this study we present the metabolic profile of highly metastatic
human melanoma cells line WM793.We demonstrate the feasibility of
characterizing in-vitro living melanoma cells by
1H-MRS with a total number of 9 metabolites quantified, covering energy markers
(Glc, Lac, Ace), amino acids (Glu, Ala) and anti-oxidant (Tau, Asc) and cell
membrane precursor (Cho).
