7T MRS AND 18F AV45 PET NEURONAL MARKERS IN ELDERLY HIV+ SUBJECTS: EFFECTS OF SEROSTATUS AND COGNITIVE IMPAIRMENT
Mona A Mohamed1, Peter B Barker1, Richard L Skolasky2, Heidi Vornbrock Roosa3, Yun Zhou1, Weiguo Ye1, Noble George1, James Brasic1, Dean F Wong1, and Ned Sacktor3
1Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, United States, 2Orthopedics, Johns Hopkins Medical Institutions, Baltimore, MD, United States, 3Neurology, Johns Hopkins Medical Institutions, Baltimore, MD, United States
In this study, 7T MRS and 18F AV45 PET were used to measure
brain metabolites and amyloid burden in Elderly HIV subjects. These reliable
biomarkers can be used in assessing the relation between normal aging, HIV and the degree of HIV Associated
Neurocognitive Disorders (HAND).
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