Abstract #2279

Comparison of Single-shot ASE and Multi-shot ASE Sequence for Measurement of Lower Extremity Muscle Oxygenation

CY Wang¹, L Jiang², R Zhang³, XD Zhang⁴, H Wang², K Zhao⁴, LX Jin², J Zhang^1,3, XY Wang^1,4, and J Fang^1,3

¹Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China, People's Republic of, ²Philips Healthcare, Suzhou, China, People's Republic of, ³College of Engineering, Peking University, Beijing, China, People's Republic of, ⁴Department of Radiology, Peking University First Hospital, Beijing, China, People's Republic of

Recently, MRI based methods for measuring muscle oxygen extraction fraction (OEF) have been reported. Asymmetric spin-echo (ASE) sequence combining with a susceptibility model is the most widely used approach. However, conventional ASE sequence uses single-shot (SS) EPI for data acquisition, which suffers from the problem of severe susceptibility artifacts and distortion due to the relatively long echo train length (ETL). One solution is to employ multi-shot (MS) EPI instead of SS EPI for data acquisition. With the use of MS-ASE technique, much higher spatial resolution could be achieved for lower extremity muscle imaging.

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