Abstract #2270

Use of Adding T2 Mapping Sequence to a Routine MR Imaging Protocol to Evaluate of the Articular Cartilage Changes of the Knee and Ankle Joint with Hemophilia in Children

Ningning Zhang¹, Yanqiu Lv¹, Kaining Shi², Di Hu¹, Huiying Kang¹, Yue Liu¹, Runhui Wu³, and Yun Peng¹

¹Imaging Center, Beijing Children's Hospital, Capital Medical University, Beijing, China, People's Republic of, ²Imaging System Clinical Science, Philips Healthcare, Beijing, China, People's Republic of, ³Hematology Center, Beijing Children's Hospital, Capital Medical University, Beijing, China, People's Republic of

T2 mapping sequences can help detect changes in the water and collagen content. This sequence have been used extensively in osteoarthritis research studies to detect disease and treatment related changes in articular cartilage(1-3). However, little is known about the early cartilage changes in hemophilia patients, and once established, arthropathy follows a progressive and non-reversible process despite the use of factor concentrates.

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