Masamitsu Hatakenaka1, Koichi Onodera1, Naomi Koyama1, and Mitsuhiro Nakanishi2
1Diagnostic Radiology, Sapporo Medical University, Sapporo, Japan, 2Division of Radiology, Sapporo Medical University Hospital, Sapporo, Japan
To
evaluate reproducibility of voxel-based ADC, voxel-based ADC of the phantom was
measured using clinical 3T MRI system. The direction of motion probing gradient
affected the voxel-based ADC significantly in both echo planar
imaging and turbo spin echo diffusion-weighted imaging. Also voxel-based ADC
differed both between identical positioning examinations and between slightly
different positioning examinations. Voxel-based ADC could not be reproduced sufficiently even in a phantom study. It would
be recommended to pay enough attention when performing voxel-based ADC study
like histogram analysis for tumor ADC.