Fabian Hilbert1, Simon Veldhoen1, Tobias Wech1, Henning Neubauer1, Thorsten Alexander Bley1, and Herbert Köstler1
Diffusion tensor imaging (DTI) accounts for
anisotropy of diffusion, while the intravoxel incoherent motion (IVIM) model
considers a fast moving pseudo-diffusion compartment. In the kidney DTI and
IVIM parameters vary significantly depending on the time they are acquired
within the cardiac cycle. A combined IVIM-DTI model incorporates anisotropic
diffusion and anisotropic pseudo-diffusion parameters. The purpose of this
study was to investigate the impact of the cardiac cycle on the combined
IVIM-DTI model. While in DTI the fractional anisotropy of the diffusion tensor
(FAD) varies within the cardiac cycle, FAD does not
change in the IVIM-DTI model.