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Abstract #1970

Liver metastasis from colorectal cancer; a comparison of reproducibility of ADC between multiple sites and vendors, at 1.5 T and 3 T

Ryan Pathak1, Neil A Thacker2, David M Morris2, Philippe Garteiser3, Sabrina Doblas3, Bernard E. Van Beers3, Houshang Amiri4, Arend Heerschap4, and Alan Jackson1

1The Wolfson Molecular Imaging Centre, University of Manchester, Manchester, United Kingdom, 2Centre for Imaging Sciences, University of Manchester, Manchester, United Kingdom, 3Laboratory of imaging biomarkers, INSERM, Paris Diderot University, Paris, France, 4Radboud University Medical Center, Nijmegen, Netherlands

ADC, calculated from diffusion-weighted MRI, is a potential quantitative imaging biomarker for detection of early treatment response. Imaging in the liver suffers from poor reproducibility, mainly as a result of respiratory motion. In this study we compare reproducibility in a multi-site, multi vendor setting at both 1.5 T and 3 T field strengths, for patients histologically diagnosed with colorectal cancer, who have radiological evidence of liver metastasis.

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