Abstract #1958

Compact and fully automated 3D multifrequency tabletop MR elastography for the measurement of viscoelastic parameters in small tissue samples

Navid Samavati^1,2, Clara Körting¹, Toni Drießle³, Stefan Wintzheimer³, Jing Guo¹, Florian Dittmann¹, Ingolf Sack¹, and Jürgen Braun²

¹Department of Radiology, Charité University Medicine, Berlin, Germany, ²Department of Medical Informatics, Charité University Medicine, Berlin, Germany, ³Pure Devices GmbH, Würzburg, Germany

A fully integrated tabletop MR elastography (MRE) system based on a 0.5-T permanent magnet for investigations of small tissue samples is introduced. A 3D spin echo MRE sequence allows control of all MRE parameters including frequency and amplitude of a piezoelectric actuator. The device enables fully automated measurements of maps of viscoelastic parameters in soft tissue samples by 3D multifrequency MRE. Initial results are in good agreement to published data and demonstrate the great potential of the system as a preclinical research unit in histopathological laboratories and operating rooms.

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