Heiko Tzschätzsch1, Jing Guo1, Florian Dittmann1, Sebastian Hirsch1, Eric Barnhill1, Jürgen Braun2, and Ingolf Sack1
1Department of Radiology, Charité - University Medicine Berlin, Berlin, Germany, 2Institute of Medical Informatics, Charité - University Medicine Berlin, Berlin, Germany
Elastography
often suffers from limited anatomical resolution due to noise and insufficient
elastic deformation. We here introduce noise-robust multifrequency wave number
inversion for multifrequency MR elastography. Compound maps of wave speed are
obtained, which reveal variations in tissue elasticity in a tomographic
fashion, i.e. an unmasked, slice-wise display of anatomical details at
pixel-wise resolution. The method is demonstrated using data from the
literature including abdominal and pelvic organs such as the liver, spleen,
uterus and cervix. Elastic parameters consistent with literature values were
obtained even in small regions with low wave amplitudes such as nucleus
pulposus and spinal cord.
