Abstract #1952

Impact of Field Strength and Image Resolution on MRE Stiffness Estimation

Eric Barnhill¹, Jing Guo², Florian Dittmann², Sebastian Hirsch², Michael Perrins³, Lucy Hiscox³, Tim Herrmann⁴, Johannes Bernarding⁴, Neil Roberts³, Jürgen Braun¹, and Ingolf Sack²

¹Institute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany, ²Department of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany, ³Clinical Research Imaging Centre, The University of Edinburgh, Edinburgh, United Kingdom, ⁴Institute for Biometrics and Medical Informatics, Otto von Guericke University Magdeburg, Magdeburg, Germany

We investigated the impact of field strength and image resolution on brain MRE stiffness results. A cohort of 18 healthy volunteer subjects was scanned at 1.5T (2mm isotropic voxels), 3T (2mm) and 7T (1mm), with a fourth set downsampling the 7T to 2mm. Means were 1634 Pa (+/-613) for 1.5T, 1743 Pa (+/-811) for 3T, 1786 (+/-634) Pa for 7T 2mm, and 927 (+/-364) Pa for 7T 1mm. In the paired sign-rank tests, there were no significant effects for field strength. Examination of histograms of example slices suggests that a different distribution of features is being captured at the higher resolution.

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