The consequences of two different zone-division
methods in MRI T2 of articular cartilage were studied, using an animal model of
early osteoarthritis (OA). By dividing the cartilage thickness unequally, significant
improvement in OA detection can be achieved – both in the deeper cartilage as
well as between the contralateral and normal tissue. This improved detection
may become important in the clinical diagnostics of early OA.