Xiaojuan TAO1, Yun PENG1, Yanqiu LV1, and Kaining SHI2
1Imaging Center of Beijing Children's Hospital Affiliated To Capital Medical University, Beijing, China, People's Republic of, 2Imaging Systems Clinical Science Philips Healthcare, Beijing, China, People's Republic of
Spleen and liver are common organs involved in
Gaucher disease (GD), while few reports have been published on the measurement
of volume and lipid content of liver and spleen using MR. This
study recruited 42 patients with GD by 1.5T MR. Our results showed
that enlargement of spleen was more severe than liver. Spleen has higher
lipid content than liver among these patients, while both of them exhibited
higher fat fraction than normal value. Our study suggests MRI can be employed
to monitor the disease progression and effect of the treatment in children and
adolescent patients with GD.
