1Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, United Kingdom, 2Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, United Kingdom
Motion corruption leads to major artefacts in fMRI which are damaging in
studies. Most processing pipelines employ linear registration of the brain
volume at each time point. As slices are acquired individually, however, it is
possible for each slice to require a different transformation. Here, we compared
the efficacy of linear volume registration, independent slice-based
registration and volume non-linear registration for retrospective correction of
fMRI acquisitions using data from forty non-cooperative patients with
substantial motion.