Combining Resting-State fMRI and Perfusion maps for potential Pre-Surgical Planning
Lalit Gupta1, Prativa Sahoo1, Pradeep K Gupta2, Indrajit Saha3, Rana Patir4, Sandeep Vaishya4, and Rakesh K Gupta2
1Philips India Ltd., Bangalore, India, 2Department of Radiology, Fortis Memorial Research Institute, Gurgaon, India, 3Philips India Ltd., Gurgaon, India, 4Department of Neurosurgery, Fortis Memorial Research Institute, Gurgaon, India
Mapping
of functionally active regions for patients with mass lesions is critical for
pre-surgical planning. We have developed an atlas based approach that
automatically select seed points from six functional regions (motor and
language regions) and computes corresponding functionally connected regions
using resting state fMRI data. Functional connectivity maps were super-imposed
on MR perfusion maps and structural images. Results were obtained from 22 brain
tumor patients. Regions near the tumor with high correlation are seen as active
regions that contribute to motor/language activities, combined with perfusion maps
may help clinicians for better surgical planning.
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