Chan Hong Moon1, Jung-Hwan Kim1,2, and Kyongtae Ty Bae1,2
1Radiology, University of Pittsburgh, Pittsburgh, PA, United States, 2Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States
Compound signal, BOLD
(e.g., de-oxygenation, CBF and CBV) has different neuronal specificity depending
on the major source. At high-field such as 7T, stimulus-evoked BOLD (fMRI) is
known to be more localized to cortex region mainly due to suppression of short
T2* signals in large draining vessels. It is question whether
spontaneous-evoked BOLD during resting status (rsfMRI) can be localized to
neural response and the correlation with fMRI activation. In this study, we
investigated BOLD source during resting status in primary motor cortex using
high-resolution 7T, and additionally the advantage of 7T rsfMRI in small-scale
brain connectivity.